November 08, 2023 4 min read

In the realm of cardiovascular health and overall well-being, the search for natural remedies that support heart health has been a timeless pursuit. Two compounds, Vitamin K2 and Nattokinase, have emerged as intriguing contenders, each offering its own unique set of potential health benefits.

Exploring the world of health supplements can be confusing, making people wonder if they really work. In this article, we'll clarify the differences between Vitamin K2 and Nattokinase, explaining what they do, how they might help your heart, and more.

Whether you're into health or just curious about natural remedies, you’re in the right place. We'll compare Vitamin K2 and Nattokinase in a simple way, so you can make smart choices for your health.

And if you're looking or a quality Nattokinase or Vitamin K2 formula, you can check out our premium formulas at Utzy Naturals.

What’s the Difference Between Vitamin K2 and Nattokinase?

Vitamin K2 and Nattokinase, though both associated with cardiovascular health, are distinct in their nature and functions.

Vitamin K2 is a fat-soluble vitamin responsible for regulating calcium metabolism. Essentially, it works to ensure that calcium is directed to the right places, such as bones and teeth, while preventing its harmful accumulation in arteries. This supports arterial flexibility and overall heart health.

On the other hand, Nattokinase is an enzyme derived from natto, a fermented soybean dish. Nattokinase's primary role is to promote healthy blood flow by breaking down fibrin, a protein involved in blood clot formation. This helps to support healthy circulation and blood flow.

While Vitamin K2 is more involved in calcium regulation, Nattokinase primarily focuses on circulation, making them complementary in their potential contributions to overall heart health.

Which Is Best, Vitamin K2 or Nattokinase?

The question of whether Vitamin K2 or Nattokinase is better is not a straightforward one, as they serve different roles in supporting heart health.

Vitamin K2 is essential for regulating calcium metabolism and preventing calcium buildup in arteries.

On the other hand, Nattokinase is primarily known for its ability to break down blood clots and support healthy blood flow.

Instead of one being better than the other, they can be complementary. Depending on your specific health needs and goals, you might consider incorporating both Vitamin K2 and Nattokinase as part of a comprehensive approach to support your heart health.

However, it's crucial to consult with a healthcare professional before adding any supplements to your regimen to determine what's most appropriate for your individual health circumstances.

Benefits of Vitamin K2:

Vitamin K2, a lesser-known fat-soluble vitamin, plays a crucial role in supporting overall health, with its most prominent benefits often associated with bone health and cardiovascular well-being.

1. Bone Health:

Vitamin K2 is instrumental inregulating calcium metabolism in the body. It works to ensure that calcium is appropriately directed to the bones and teeth, contributing to bone mineralization and density.

This function is particularly vital in helping to support stronger bones, which is important for healthy aging.Studies suggest that adequate Vitamin K2 intake is associated with a lower risk of bone fractures and improved bone health.

2. Heart Health:

Beyond bone health, Vitamin K2 plays a significant role in cardiovascular well-being.Research indicates that it helps prevent the buildup of calcium in arterial walls, which helps to support arterial flexibility

By ensuring that calcium is deposited in the bones and teeth rather than accumulating in arteries, Vitamin K2 supports healthy blood vessels, ultimately supporting overall cardiovascular function.

3. Dental Health:

Vitamin K2 is a silent hero when it comes to dental health. It plays a pivotal role in regulating calcium metabolism, ensuring that calcium is directed to the teeth, strengthening tooth enamel, and preventing its harmful buildup in soft tissues.

This precise calcium regulation helps to regulate tooth decay, which is essential for overall oral health.

You can read more about vitamin K2 in our in-depth guide here.

Benefits of Nattokinase:

Nattokinase, an enzyme derived from the traditional Japanese food natto, has gained recognition for its potential health benefits, particularly in the context of cardiovascular well-being.

Here are some of the key health benefits of Nattokinase:

1. Healthy Clotting Function:

One of the primary functions of Nattokinase is its ability tobreak down fibrin, a protein involved in the formation of blood clots. By supporting fibrinolysis, Nattokinase assists normal clotting function.

2. Healthy Circulation:

Nattokinase's fibrinolytic activity not only prevents blood clot formation but also supports healthy blood flow. By breaking down clots and preventing their reformation, Nattokinase can support healthy blood circulation.

3. Health Blood Pressure Levels:

Someresearch suggests that Nattokinase may help to support healthy blood pressure levels effect. It is believed to help relax and dilate blood vessels, contributing to improved blood pressure control.

Read more about the health benefits of nattokinase here.

How to Add These Supplements to Your Routine?

If you’re considering adding a vitamin K2 or nattokinase supplement to your routine, there are a few thighs to consider.

First, ensure that the product is tested for purity and potency.

Second, make sure that the dosing is correct. As an example, for nattokinase, you typically want to look for a product that contains 2,000 fibrinolytic units per serving. 

Third, consider the source and form of the supplement. Vitamin K2 can come in various forms, such as MK-4 and MK-7, and the source can be derived from animal or plant-based sources. Depending on your dietary preferences and health needs, you may want to choose a specific form or source of vitamin K2 that suits you best.

At Utzy Naturals, we have bothvitamin K2 formulas and anattokinase formula available. Our products are tested for purity and potency, dosed according to research, and included in the form that’s best for absorption and utilization.


In summary, Vitamin K2 and Nattokinase offer distinct health benefits. Vitamin K2 supports bone, heart, and dental health, while Nattokinase helps prevent blood clots, enhances circulation, and may regulate blood pressure.

The choice between them depends on your specific health needs, and it's important to consult a healthcare professional for guidance. By making informed decisions, you can promote your overall well-being.

Daniel Powers, MS
Daniel Powers (co-founder of Utzy Naturals) is a health fanatic and writer. He's obsessed with learning how to live a healthier, happier life and sharing his knowledge with others.


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